ManifoldUncategorizedUpdated 13m ago

Will the TRIAD trial report that rapamycin significantly extended lifespan in dogs by December 31, 2031?

As of Oct 1, 2026, 4:22 PM ET, Manifold priced this market at 45.1% (down from 50.0% 24 hours earlier). It had Ṁ100 traded in the past 24 hours and Ṁ2.1K of order-book liquidity. probcast.co rates the support behind this price as weak.

Market probability
45.1%
−4.9 percentage points
over 24 hours50.0% → 45.1%
1917 days until the event deadline
Deadline: December 31, 2031 at 6:59 PM ET

The move lacks solid trading support — treat the new probability with caution.

The pricing has weak support: moderate trading volume.

How credible was the move?

Three separate questions — a move can be genuine while the latest price is still settling. Methodology →

Move validity

Is the move backed by real trading and depth?

Weak

The pricing has weak support: moderate trading volume.

Consensus stability

Has the market settled at the new probability?

Forming

Movement has slowed (4.9 points over six hours) but the market has not fully settled.

Contract clarity

Will the rules resolve without ambiguity?

Medium

Moderate resolution risk, driven mainly by no resolution basis.

Recent trade activity$100 traded

From the latest trade tape (most recent 200 prints) — a live activity sample, not a lifetime total.

Why the odds moved

The probability fell 4.9 percentage points over the last 24 hours (50.0% → 45.1%).

No verified catalyst has been linked to this move yet. ProbCast does not attribute moves to news without evidence connecting the timing of a specific report to the repricing.

What could move this market next?

  • The market's deadline arrivesDecember 31, 2031 at 6:59 PM ET

    The contract must resolve based on what has happened by this date.

Derived from the contract's own mechanics as of Oct 1, 4:34 PM ET. ProbCast does not list scheduled meetings, announcements, or data releases it cannot verify.

Advanced analysis (experimental)

Research signals — these models are still accumulating the history needed for full validation, and they can disagree with the headline read. Model confidence: low · expected error ±26 pts.

One big traderLegacy movement classifier: noisy

What's happening

high classifier confidence
One big trader

Recent movement was driven largely by one participant with little broad follow-through. The move may not represent consensus.

  • One participant drove 100% of recent flow
  • Move not broadly confirmed (1 participants)

Read with caution —Read the latest price with caution; conditions make it an unreliable summary right now.

More details — reliability score, dynamics, durability
Reliability score
11Low
Where the price path tends to go next1049 observed
  • Illiquid / quiet99%

Short-term motion of the price line (~1h), distinct from the environment above — not a prediction of the final outcome.

DurabilityMedium· half-life ~1h
PredictabilityStable

Secondary read: leaning toward Reacting to news.

A read-only classification of the market environment — how much weight the current price deserves as a read of consensus. It describes conditions, never a trade.

Market data

24h volume

Ṁ100

Liquidity

Ṁ2.1K

Total volume

Ṁ100

Category
Uncategorized
Venue
Manifold
Open interest
—
Current probability
45.1%
7-day range
45.1% – 50.0%
Resolves
Dec 31, 2031
Change (pts)1H0.06H-4.924H-4.97D-4.9