ManifoldUncategorizedUpdated 10m ago

Will the FDA approve any drug for an aging indication in humans before January 1, 2035?

As of Oct 1, 2026, 4:22 PM ET, Manifold priced this market at 11.9% (down from 40.0% 24 hours earlier). It had Ṁ176.5 traded in the past 24 hours and Ṁ2.1K of order-book liquidity. probcast.co rates the support behind this price as weak.

Market probability
11.9%
−28.1 percentage points
over 24 hours40.0% → 11.9%
3013 days until the event deadline
Deadline: December 31, 2034 at 6:59 PM ET

The move lacks solid trading support — treat the new probability with caution.

The pricing has weak support: healthy trading volume and market depth.

How credible was the move?

Three separate questions — a move can be genuine while the latest price is still settling. Methodology →

Move validity

Is the move backed by real trading and depth?

Weak

The pricing has weak support: healthy trading volume and market depth.

Consensus stability

Has the market settled at the new probability?

Forming

Movement has slowed (28.1 points over six hours) but the market has not fully settled.

Contract clarity

Will the rules resolve without ambiguity?

High

The resolution rules are relatively specific, with a named source and a defined deadline.

Recent trade activity$176.5 traded

From the latest trade tape (most recent 200 prints) — a live activity sample, not a lifetime total.

Why the odds moved

The probability fell 28.1 percentage points over the last 24 hours (40.0% → 11.9%).

No verified catalyst has been linked to this move yet. ProbCast does not attribute moves to news without evidence connecting the timing of a specific report to the repricing.

What could move this market next?

  • The market's deadline arrivesDecember 31, 2034 at 6:59 PM ET

    The contract must resolve based on what has happened by this date.

Derived from the contract's own mechanics as of Oct 1, 4:32 PM ET. ProbCast does not list scheduled meetings, announcements, or data releases it cannot verify.

Advanced analysis (experimental)

Research signals — these models are still accumulating the history needed for full validation, and they can disagree with the headline read. Model confidence: low · expected error ±30 pts.

Reacting to newsLegacy movement classifier: noisy

What's happening

high classifier confidence
Reacting to news

The price is actively repricing on real volume. The number is still moving — don't treat the latest print as settled consensus yet.

  • Probability moved 28.1 pts in ≤6h on adequate liquidity

Read the latest price with caution; conditions make it an unreliable summary right now.

More details — reliability score, dynamics, durability
Reliability score
3Low
Where the price path tends to go next1049 observed
  • Illiquid / quiet99%

Short-term motion of the price line (~1h), distinct from the environment above — not a prediction of the final outcome.

DurabilityMedium· half-life <1h
PredictabilityElevated irreducibility

Secondary read: leaning toward One big trader.

A read-only classification of the market environment — how much weight the current price deserves as a read of consensus. It describes conditions, never a trade.

Market data

24h volume

Ṁ176.5

Liquidity

Ṁ2.1K

Total volume

Ṁ0

Category
Uncategorized
Venue
Manifold
Open interest
—
Current probability
11.9%
7-day range
11.9% – 40.0%
Resolves
Dec 31, 2034
Change (pts)1H0.06H-28.124H-28.17D-28.1